齐海山

现任职称/职务：副教授
通讯地址：北洋园校区54-329
电子邮箱：hsqi@tju.edu.cn
办公电话：

论著专利:

[1]      Qi HS, Du Y, Hu G, Zhang L*, Poly(carboxybetaine methacrylate)-functionalized magnetic composite particles: A biofriendly support for lipase immobilization. International Journal of Biological Macromolecules. doi.org/10.1016/j.ijbiomac.2017.10.150. 

[2]      Qi HS, Du Y, Zhou X, Zheng WW, Zhang L*, Wen JP, Liu LM, Engineering a new metabolic pathway for itaconate production in Pichia stipitis from xylose. Biochemical Engineering Journal, 2017, 126: 101–108.

[3]      Qi HS, Lv MM, Song KJ, Wen JP*, Integration of parallel ¹³C-labeling experiments and in silico pathway analysis for enhanced production of ascomycin. Biotechnology and Bioengineering, 2017, 114: 1036–1044.

[4]      Liu J#, Qi HS#,  Wang C, Wen JP*, Model-driven intracellular redox status modulation for increasing isobutanol production in Escherichia coli. Biotechnology for Biofuels, 2015, 8:108. 

[5]      Qi HS, Zhao SM, Fu H, Wen JP*, Jia XQ, Coupled cell morphology investigation and metabolomics analysis improves rapamycin production in Streptomyces hygroscopicus. Biochemical Engineering Journal, 2014, 91: 186-195. 

[6]      Pan XR#, Qi HS#, Mu L, Wen JP*, Jia XQ, Comparative Metabolomic-Based Metabolic Mechanism Hypothesis for Microbial Mixed Cultures Utilizing Cane Molasses Wastewater for Higher 2-Phenylethanol Production. Journal of Agricultural and Food Chemistry, 2014, 62:9927-9935. 

[7]      Qi HS, Li SS, Zhao SM, Huang D, Xia ML, Wen JP*, Model-driven redox pathway manipulation for improved isobutanol production in Bacillus subtilis complemented with experimental validation and metabolic profiling analysis. PLOS ONE, 2014, 9(4): e93815.

[8]      Qi HS, Zhao SM, Wen JP*, Chen YL, Jia XQ, Analysis of ascomycin production enhanced by shikimic acid resistance and addition in Streptomyces hygroscopicus var. ascomyceticus. Biochemical Engineering Journal, 2014, 82: 124-133. 

[9]      Qi HS, Zhao SM, Fu H, Wen JP*, Jia XQ, Enhancement of ascomycin production in Streptomyces hygroscopicus var. ascomyceticusby combining resin HP20 addition and metabolic profiling analysis. Journal of Industrial Microbiology & Biotechnology, 2014, 41(9):1365-1374.

[10]  Qi HS, Xin X, Li SS Wen JP*, Chen YL, Jia XQ, Higher-level production of ascomycin (FK520) by Streptomyces hygroscopicus var. ascomyceticus irradiated by femtosecond laser, Biotechnology and Bioprocess Engineering, 2012, 17 (4): 770-779. 

[11]  Wang GY, Huang D, Qi HS, Wen JP*, Jia XQ, Rational medium optimization based on comparative metabolic profiling analysis to improve fumaric acid production. Bioresource Technology, 2013, 137:1-8. 

[12]  Zhao SM, Huang D, Qi HS, Wen JP*, Jia XQ, Comparative metabolic profiling-based improvement of rapamycin production by Streptomyces hygroscopicus. Applied Microbiology and Biotechnology. 2013, 97:5329-41.

[13]  Xin X, Qi HS, Wen JP*, Jia XQ, Chen YL, Reduction of foaming and enhancement of ascomycin production in rational Streptomyces hygroscopicus fermentation. Chinese journal of chemical engineering, 2015, 23(7):1178-1182. 

[14]  Wei L, Liu J, Qi HS, Wen JP*, Engineering Scheffersomyces stipitis for fumaric acid production from xylose. Bioresource Technology. 2015, 187, 246-254. 

[15]  Song KJ, Wei L, Liu J, Wang JH, Qi HS, Wen JP, Engineering of the LysR family transcriptional regulator FkbR1 and its target gene to improve ascomycin production. Applied Microbiology and Biotechnology. 2017, 101:4581-92.