SCHOOL OF CHEMICAL ENGINEERING

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教授

史清洪

现任职称/职务:教授
通讯地址:天津市津南区海河教育园区雅观路135号 天津大学北洋园校区54楼E363室
电子邮箱:qhshi@tju.edu.cn
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论著专利:

代表性论文

(1) Shi Q. H., Tian Y., Dong X. Y., Bai S., Sun Y. Chitosan-coated silica beads as immobilized metal affinity support for protein adsorption [J]. Biochemical Engineering Journal, 2003, 16 (3): 317-322.

(2) Shi Q.-H., Zhou Y., Sun Y. Influence of pH and ionic strength on the steric mass-action model parameters around the isoelectric point of protein [J]. Biotechnology Progress, 2005, 21 (2): 516-523.

(3) Shi Q.-H., Zhou X., Sun Y. A novel superporous agarose medium for high-speed protein chromatography [J]. Biotechnology and Bioengineering, 2005, 92 (5): 643-651.

(4) Shi Q.-H., Cheng Z., Sun Y. 4-(1H-imidazol-1-yl) aniline: A new ligand of mixed-mode chromatography for antibody purification [J]. Journal of Chromatography A, 2009, 1216 (33): 6081-6087.

(5) Shi Q.-H., Shen F.-F., Sun S. Studies of Lysozyme Binding to Histamine as a Ligand for Hydrophobic Charge Induction Chromatography [J]. Biotechnology Progress, 2010, 26 (1): 134-141.

(6) Shi Q.-H., Jia G.-D., Sun Y. Dextran-grafted cation exchanger based on superporous agarose gel: Adsorption isotherms, uptake kinetics and dynamic protein adsorption performance [J]. Journal of Chromatography A, 2010, 1217 (31): 5084-5091.

(7) Shi Q.-H., Jia G.-D., Sun Y. Process intensification of immobilized metal affinity chromatography with longitudinal and oscillatory transverse electric fields [J]. Separation and Purification Technology, 2011, 77 (3): 375-381.

(8) Yu L.-L., Shi Q.-H., Sun Y. Effect of dextran layer on protein uptake to dextran-grafted adsorbents for ion-exchange and mixed-mode chromatography [J]. Journal of Separation Science, 2011, 34 (21): 2950-2959.

(9) Shi Q.-H., Shi Z.-C., Sun Y. Dynamic behavior of binary component ion-exchange displacement chromatography of proteins visualized by confocal laser scanning microscopy [J]. Journal of Chromatography A, 2012, 1257: 48-57.

(10) Liang J., Fieg G., Shi Q.-H., Sun Y. Single and binary adsorption of proteins on ion-exchange adsorbent: The effectiveness of isothermal models [J]. Journal of Separation Science, 2012, 35 (17): 2162-2173.

(11) Shi Q.-H., Jia G.-D., Xu L., Sun Y. Effect of electric field on the partitioning behavior of solutes in entropic interaction chromatography [J]. Journal of Separation Science, 2013: doi: 10.1002/jssc.201300297

论著:

(1) 史清洪, 赵学明. 产品的回收和纯化, in: Shuler M.L., Kargi F. (Eds), Bioprocess Engineering: Basic Concepts (译), 化工出版社, 北京, 2008, 223-258

(2) Sun Y., Liu F.-F., Shi Q.-H. Approaches to High-Performance Preparative Chromatography of Proteins. In: Zhong J.-J., Bai F.-W., Zhang W (eds), Biotechnology in China I: From Bioreaction to Bioseparation and Bioremediation. Springer, Heidelberg, 2009, volume 113, 217-254

 (3) Sun Y., Shi Q.-H., Zhang L., Zhao G.-F., Liu F.-F. Downstream Processing and Product Recovery | Adsorption and Chromatography. In: Murray Moo-Young (ed.), Comprehensive Biotechnology (Second Edition), Elsevier, New York, 2011, volume 2, 665–679

授权专利

(1) 孙彦,周鑫,史清洪,董晓燕,白姝:高容量大孔琼脂糖凝胶介质的制备方法,中国发明专利,ZL03130027.8

(2) 孙彦,周鑫,史清洪,白姝,董晓燕:高密度核材表面包裹琼脂糖凝胶薄壳介质的制备方法,中国发明专利,ZL 03129755.2

(3) 孙彦,赵雪雁,张磊,史清洪,董晓燕,白姝:利用膨胀床色素亲和色谱纯化重组人干扰素α-2b 的方法,中国发明专利,ZL 200310106725.0

(4) 孙彦,孙国勇,史清洪,董晓燕,白姝:双乳化法制备两类孔型刚性高分子介质的方法,中国发明专利,ZL 200410019065.7

(5) 孙彦,孙国勇,董晓燕,白姝,史清洪:以碳酸钙微粒悬浮液制备超大孔型刚性高分子介质的方法,中国发明专利,ZL 200510013278.3

(6) 孙彦,谭国民,史清洪,董晓燕,白姝:制备型横向电场的体积排阻电色谱分离生物大分子的方法,中国发明专利,ZL 200510014695.X

(7) 孙彦,王冬梅,史清洪,董晓燕,白姝:超大孔纤维素微球蛋白质吸附介质的制备方法,中国发明专利,ZL 200710056590.X

(8) 史清洪,程征,孙彦,董晓燕,白姝:用于免疫球蛋白类蛋白质分离纯化的色谱介质及其制备方法,中国发明专利,ZL 200710059576.5

(9) 徐亮,董晓燕,史清洪,白姝,孙 彦:阴离子聚合物接枝涂层毛细管及用于蛋白质在线富集分析方法,中国发明专利,ZL 200810151254.8

(10) 徐亮,孙 彦,史清洪,白姝,董晓燕:聚乙烯醇涂层毛细管的制备方法及应用,中国发明专利,ZL 200910067986.3