1.      Zhao Fanglong, Bai Peng, Nan Weihua, Li Dashuai, Zhang Chuanbo, Lu Chunzhe, Qi Haishan, Lu Wenyu*. A modular engineering strategy for high-level production of protopanaxadiol from ethanol by Saccharomyces cerevisiae [J]. AIChE Journal, 2019, 65(3): 866-874.

2.      Sun Jie, Zhang Chuanbo, Nan Weihua, Li Dashuai, Ke Di, Lu Wenyu*. Glycerol improves heterologous biosynthesis of betulinic acid in engineered Yarrowia lipolytica[J]. Chemical Engineering Science, 2019, 196: 82-90.

3.      Liu S, Diao N, Wang Z, et al. Modular engineering of the flavin pathway in Escherichia coli for improved flavin mononucleotide and flavin adenine dinucleotide production[J]. Journal of agricultural and food chemistry, 2019. 67(23): 6532-6540.

4.      Zhao Fanglong, Zhang Chuanbo, Nan Weihua, Lu Wenyu*. An integrated bioprocess for fermentative production of protopanaxadiol by recycling ethanol waste during down-stream extraction process[J]. Journal of Cleaner Production, 2019, 234: 1-8.

5.      Liu Jingjing, Zhang Chuanbo, Lu Wenyu*. Biosynthesis of long-chain ω-hydroxy fatty acids by engineered Saccharomyces cerevisiae[J]. Journal of agricultural and food chemistry, 2019, 67(16): 4545-4552

6.      Zhang Chuanbo, Ju Haiyan, Lu Chun-Zhe, Zhao Fanglong, Liu Jingjing, Guo Xiaoyan, Wu Yufen, Zhao Guang-Rong, Lu Wenyu*. High-titer production of 13-R manoyl oxide in metabolically engineered Saccharomyces cerevisiae [J]. Microbial cell factories, 2019, 18(1): 73-81

7.      Jia Dan, Xu Shuo, Sun Jie, Zhang Chuanbo, Li Dashuai, Lu Wenyu*. Yarrowia lipolytica construction for heterologous synthesis of α-santalene and fermentation optimization[J]. Applied Microbiology and Biotechnology, 2019, 103(8): 3511-3520.

8.      Li Dashuai, Wu Yufen, Zhang Chuanbo, Sun Jie, Zhou Zhijiang, Lu Wenyu*. Production of triterpene ginsenoside compound K in the nonconventional yeast Yarrowia lipolytica [J]. Journal of Agricultural and Food Chemistry, 2019, 67(9): 2581–2588.

9.      Wu Yufen, Xu Shuo, Gao Xiao, Li Man, Li Dashuai, Lu Wenyu*. Enhanced protopanaxadiol production from xylose by engineered Yarrowia lipolytica [J]. Microbial Cell Factories, 2019, 18(1): 83-94.

10.   Guo Xiaoyan, Liu Jingjing, Zhang Chuanbo, Zhao Fanglong, Lu Wenyu*. Stepwise increase in the production of 13R-manoyl oxide through metabolic engineering of Saccharomyces cerevisiae [J]. Biochemical Engineering Journal, 2019, 144: 73-80.

11.   Lu Wenyu, Zhu Baozhong, Jia Xiaoqiang*; Development and Optimization of Oil Spill Dispersant for High Viscosity Oil Spill; Transactions of Tianjin University; 52(1); 2019; 26-32.

12.   Tan Jinxiu, Yang Xiaona, Lu Wenyu*. Research of 1, 3-dihydroxyacetone production by overexpressing glycerol transporter and glycerol dehydrogenase[J]. Transactions of Tianjin University, 2019, 1-10.


13.   Zhang Chuanbo, Liu Jingjing, Zhao Fanglong, Lu Chunzhe, Zhao Guang-Rong Lu Wenyu*. Production of sesquiterpenoid zerumbone from metabolic engineered Saccharomyces cerevisiae[J]. Metabolic Engineering, 2018, 49: 28-35.

14.   Lu Chun-Zhe, Zhang Chuanbo, Zhao Fanglong, Li Dashuai, Lu Wenyu*. Biosynthesis of ursolic acid and oleanolic acid in Saccharomyces cerevisiae [J]. AIChE Journal, 2018, 64(11): 3794-3802.

15.   Gao Xiao, Caiyin Qinggele, Zhao Fanglong, Yufen Wu, Lu Wenyu*. Engineering Saccharomyces cerevisiae for enhanced production of protopanaxadiol with cofermentation of glucose and xylose[J]. Journal of Agricultural and Food Chemistry, 2018. 66(45): 12009–12016.

16.   Liu Ting, Zhang Chuanbo, Lu Wenyu*. Heterologous production of levopimaric acid in Saccharomyces cerevisiae [J]. Microbial cell factories, 2018, 17 (1): 114-123.

17.   Guo Xiaoyan, Sun Jie, Li Dashuai, Lu Wenyu*. Heterologous biosynthesis of (+)-nootkatone in unconventional yeast Yarrowia lipolytica[J]. Biochemical Engineering Journal, 2018, 137: 125-131.

18.   Zhang Yaguang, Jia Dan, Sun Wanqi, Yang Xue, Zhang Chuanbo, Zhao Fanglong, Lu Wenyu*. Semicontinuous sophorolipid fermentation using a novel bioreactor with dual ventilation pipes and dual sieve‐plates coupled with a novel separation system[J]. Microbial biotechnology, 2018, 11(3): 455-464.

19.   Ke Di, Caiyin Qinggele, Zhao Fanglong, Liu Ting, Lu Wenyu*. Heterologous biosynthesis of triterpenoid ambrein in engineered Escherichia coli[J]. Biotechnology letters, 2018, 40(2): 399-404.

20.   Zhang Chuanbo, Ke Di, Duan Yuejiao, Lu Wenyu*. The combinatorial biosynthesis of “unnatural” products with polyketides[J]. Transactions of Tianjin University, 2018, 24(6): 501-512.

21.   Liu Zhen, Wang Yiting, Jia Xiaoqiang, Lu Wenyu*. Isolation of secondary metabolites with antimicrobial activities from Bacillus amyloliquefaciens LWYZ003[J]. Transactions of Tianjin University, 2018, 25 (1): 1-7.


22.   Zhao Fanglong, Du Yanhui, Bai Peng, Liu Jingjing, Lu Wenyu*, Yuan Yingjin. Enhancing Saccharomyces cerevisiae reactive oxygen species and ethanol stress tolerance for high-level production of protopanoxadiol[J]. Bioresource technology, 2017, 227: 308-316.

23.   Lu Chunzhe, Yin Jin, Zhang Chuanbo, Lu Wenyu*. Fed-Batch Fermentation for Spinosad Production in an Improved Reactor[J]. Transactions of Tianjin University, 2017, 23(6): 530-537.

24.   Ting Liu,Xiangmei Zhang,Fanglong Zhao, Lu Wenyu*.Molecular simulation and catalytic active sites identification of dammarenediol-Ⅱ synthase[J].Journal of Beijing Institute of Technology, 2017, 26(04):563-570.

25.   Lu Chunzhe, Yin Jin, Zhao Fanglong, Li Feng Lu Wenyu*. Metabolomics analysis of the effect of dissolved oxygen on spinosad production by Saccharopolyspora spinosa[J]. Antonie van Leeuwenhoek, 2017, 110 (5): 677-685.


26.   Zhao Fanglong, Bai Peng, Liu Ting, Li Dashuai, Zhang xiangmei, Lu Wenyu*, Yuan Yingjin.. Optimization of a cytochrome P450 oxidation system for enhancing protopanaxadiol production in Saccharomyces cerevisiae[J]. Biotechnology and bioengineering, 2016, 113(8): 1787-1795.

27.   Li Dashuai, Zhang Qiang, Zhou Zhijiang, Zhao Fanglong Lu Wenyu*. Heterologous biosynthesis of triterpenoid dammarenediol-II in engineered Escherichia coli[J]. Biotechnology letters, 2016, 38(4): 603-609.


28.   Lin Fujian, Guo Xiaoyan, Lu Wenyu*. Efficient biotransformation of ginsenoside Rb1 to Rd by isolated Aspergillus versicolor, excreting β-glucosidase in the spore production phase of solid culture[J]. Antonie van Leeuwenhoek, 2015, 108(5): 1117-1127.

29.   Zhang Chuanbo, Xue Chaoyou, Shen Yueqi, Lu Wenyu*. Selection of reference genes in Saccharopolyspora spinosa for real-time PCR[J]. Transactions of Tianjin University, 2015, 21(5): 461-467.

30.   Zhao Fanglong, Zhang Chuanbo, Yin Jin, Shen Yueqi Lu Wenyu*. Coupling of spinosad fermentation and separation process via two-step macroporous resin adsorption method[J]. Applied biochemistry and biotechnology, 2015, 176(8): 2144-2156.

31.   Hu Cheng, Lu Wenyu*. Insight into yeast: a study model of lipid metabolism and terpenoid biosynthesis[J]. Biotechnology and applied biochemistry, 2015, 62(3): 323-328.


32.   Wu Xinsen, Wang Xiaoyang, Lu Wenyu*. Genome-scale reconstruction of a metabolic network for Gluconobacter oxydans 621H[J]. Biosystems, 2014, 117: 10-14.

33.   Wang Xiaoyang, Zhang Chuanbo, Wang Meiling, Lu Wenyu*. Genome-scale metabolic network reconstruction of Saccharopolyspora spinosa for Spinosad Production improvement[J]. Microbial cell factories, 2014, 13(1): 41-47.

34.   Zhang Xiangmei, Xue Chaoyou, Zhao Fanglong, Li Dashuai, Yin Jing, Zhang Chuanbo, Caiyin Qinggele, Lu Wenyu*. Suitable extracellular oxidoreduction potential inhibit rex regulation and effect central carbon and energy metabolism in Saccharopolyspora spinosa[J]. Microbial cell factories, 2014, 13(1): 98-108.


35.   Xue Chaoyou, Duan Yuejiao, Zhao Fanglong, Lu Wenyu*. Stepwise increase of spinosad production in Saccharopolyspora spinosa by metabolic engineering[J]. Biochemical engineering journal, 2013, 72: 90-95.

36.   Zhao Fanglong, Xue Chaoyou, Wang Meiling, Wang Xiaoyang Lu Wenyu*. A comparative metabolomics analysis of Saccharopolyspora spinosa WT, WH124, and LU104 revealed metabolic mechanisms correlated with increases in spinosad yield[J]. Bioscience, biotechnology, and biochemistry, 2013, 77(8): 1661-1668.

37.   Xue Chaoyou, Zhang Xiangmei, Yu Zhirui, Zhao Fanglong, Wang Meiling, Lu Wenyu*. Up-regulated spinosad pathway coupling with the increased concentration of acetyl-CoA and malonyl-CoA contributed to the increase of spinosad in the presence of exogenous fatty acid[J]. Biochemical engineering journal, 2013, 81: 47-53.


38.   Zhu Lingqing, Yang Xue, Xue Chaoyou, Chen Yu, Qu Liang Lu Wenyu*. Enhanced rhamnolipids production by Pseudomonas aeruginosa based on a pH stage-controlled fed-batch fermentation process[J]. Bioresource technology, 2012, 117: 208-213.

39.   Yang Xue, Zhu Lingqing, Xue Chaoyou, Chen Yu, Qu Liang Lu Wenyu*. Recovery of purified lactonic sophorolipids by spontaneous crystallization during the fermentation of sugarcane molasses with Candida albicans O-13-1[J]. Enzyme and microbial technology, 2012, 51(6): 348-353.

40.   Wu Xinen, Xia Zhendong, Yang Xue, Xue Chaoyou Lu Wenyu*. Molecular simulation of pyrroloquinoline quinine-dependent glycerol dehydrogenase in Gluconobacter oxydans[J]. Molecular Simulation, 2012, 38(12): 1010-1014.

Before 2011

41.   Lu Wenyu,Fan Jinghua,Wen Jianping,Xia Zhendong,Caiyin Qinggele,Kinetic Analysis and Modeling of Daptomycin Batch Fermentation by Streptomyces roseosporus,Applied Biochemistry and Biotechnology,2011,163(4):453-462.

42.   Lu Wenyu,Wen Jianping,Jia Xiaoqiang,Sun Bing,Chen Yu,Liu Minhui. Effect of He-Ne laser irradiation on hydrogen production by Enterobacter aerogenes,International Journal of Hydrogen Energy,2008,33(1):34-42.

43.   Lu Wenyu,Wen Jianping,Chen Yu,Sun Bing,Jia Xiaoqiang,Liu Minghui,Caiyin Qinggele,Synergistic effect of Candida maltosa HY-35 and Enterobacter aerogenes W-23 on hydrogen production,International Journal of Hydrogen Energy,2007,32(8):1059-1066.


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2.     卢文玉,王晓阳,张传波,刺糖多孢菌基因组尺度代谢网络模型及构建方法及应用,专利号:ZL201310756418.0

3.     卢文玉,王美玲,赵方龙,一种多杀菌素的发酵方法,专利号:ZL201310756416.1

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7.     卢文玉,赵方龙.一种能提高达玛烯二醇转化效率的融合蛋白质及构建方法及应用, 专利号:ZL201410735927.X

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9.     卢文玉,张亚光,杨雪. 一种槐糖脂发酵生物分离系统及方法,中国发明专利,专利号:ZL201610343815.9

10.   卢文玉,林福建,郭校燕,一种转化人参皂苷Rb1生产Rd的曲霉及应用,专利号:ZL201510543267x