元英进

现任职称/职务：教授/副校长
通讯地址：天津市南开区卫津路92号
电子邮箱：yjyuan@tju.edu.cn
办公电话：

论著专利:

已经发表学术论文200余篇，申请专利130余项，授权专利90余项。

部分代表论文如下：

1.       Bug mapping and fitness testing of chemically synthesized chromosome X. Yi Wu#, Bingzhi Li#, Meng Zhao, Leslie A. Mitchell, Zexiong Xie, Qiuhui Lin, Xia Wang, Wenhai Xiao, Ying Wang, Xiao Zhou, Hong Liu, Xia Li, Mingzhu Ding, Duo Liu, Lu Zhang, Baoli Liu, Xiaole Wu, Feifei Li, Xiutao Dong, Bin Jia, Wenzheng Zhang, Guozhen Jiang, Yue Liu, Xue Bai, Tianqing Song, Yan Chen, Sijie Zhou, Ruiying Zhu, Feng Gao, Zheng Kuang, Xuya Wang, Michael Shen, Kun Yang, Giovanni Stracquadanio, Sarah M. Richardson, Yicong Lin, Lihui Wang, Roy Walker, Yisha Luo, Pingsheng Ma, Huanming Yang, Yizhi Cai, Junbiao Dai, Joel S. Bader, Jef D. Boeke, Jef D. Boeke, Yingjin Yuan*.2017, Science, Vol 355, Issue 6329: eaaf4706.

2.       “Perfect” designer chromosome V and behavior of a ring derivative. Zexiong Xie^#, Bingzhi Li^#, Leslie A. Mitchell, Yi Wu, Xin Qi, Zhu Jin, Bin Jia, Xia Wang, Boxuan Zeng, Huimin Liu, Xiaole Wu, Qi Feng, Wenzheng Zhang, Wei Liu, Mingzhu Ding, Xia Li, Guangrong Zhao, Jianjun Qiao, Jingsheng Cheng, Meng Zhao, Zheng Kuang, Xuya Wang, J. Andrew Martin, Giovanni Stracquadanio, Kun Yang, Xue Bai, Juan Zhao, Menglong Hu, Qiuhui Lin, Wenqian Zhang, Minghua Shen, Si Chen, Wan Su, Enxu Wang, Rui Guo, Fang Zhai, Xuejiao Guo, Haoxing Du, Jiaqing Zhu, Tianqing Song, Junjun Dai, Feifei Li, Guozhen Jiang, Shilei Han, Shiyang Liu, Zhichao Yu, Xiaona Yang, Ken Chen, Cheng Hu, Dashuai Li, Nan Jia, Yue Liu, Linting Wang, Su Wang, Xiaotong Wei, Meiqing Fu, Lanmeng Qu, Siyu Xin, Ting Liu, Kairen Tian, Xuenan Li, Jinhua Zhang, Lixiang Song, Jingui Liu, Jiafei Lv, Hang Xu, Ran Tao, Yan Wang, Tingting Zhang, Yexuan Deng, Yiran Wang, Ting Li, Guangxin Ye, Xiaoran Xu, Zhengbao Xia, Wei Zhang, Shilan Yang, Yilin Liu, Wenqi Ding, Zhenning Liu, Junqi Zhu, Ningzhi Liu, Roy Walker, Yisha Luo, Yun Wang, Yue Shen, Huanming Yang, Yizhi Cai, Pingsheng Ma, Chunting Zhang, Joel S. Bader, Jef D. Boeke, Yingjin Yuan*. 2017, Science, Vol 355, Issue 6329: eaaf4704.

3.       Precise control of SCRaMbLE in synthetic haploid and diploid yeast. Bin Jia^#, Yi Wu^#, Bingzhi Li^#, Leslie A. Mitchell, Hong Liu, Shuo Pan, Juan Wang, Haoran Zhang, Nan Jia, Bo Li, Michael Shen, Zexiong Xie, Duo Liu, Yingxiu Cao, Xia Li, Xiao Zhou, Hao Qi, Jef D. Boeke, Yingjin Yuan*. 2018, Nature Communications, Vol 9: 1933.

4.       Ring synthetic chromosome V SCRaMbLE. Juan Wang^#, Zexiong Xie^#, Yuan Ma, Xiangrong Chen, Yaoqing Huang, Bo He, Bin Jia, Bingzhi Li, Yingjin Yuan*. 2018, Nature Communications, Vol 9: 3783.

5.       An artificial chromosome for data storage. Weigang Chen^#, Mingzhe Han^#, Jianting Zhou^#, Qi Ge, Panpan Wang, Xinchen Zhang, Siyu Zhu, Lifu Song, Yingjin Yuan*. 2021, National Science Review, Vol 8, Issue 5: nwab028.

6.       Robust data storage in DNA by de Bruijn graph-based de novo strand assembly. Lifu Song, Feng Geng, Ziyi Gong, Xin Chen, Jijun Tang, Chunye Gong, Libang Zhou, Rui Xia, Mingzhe Han, Jingyi Xu, Bingzhi Li*, Yingjin Yuan*. 2022, Nature Communications,  Vol 13: 5361.

7.       RADOM, an efficient in vivo method for assembling designed DNA fragments up to 10 kb long in Saccharomyces cerevisiae. Qiuhui Lin^#, Bin Jia^#, Leslie A. Mitchell, Jingchuan Luo, Kun Yang, Karen I. Zeller, Wenqian Zhang, Zhuwei Xu, Giovanni Stracquadanio, Joel S. Bader, Jef D. Boeke, Yingjin Yuan*. 2015, ACS Synthetic Biology, Vol 4, Issue 3: 213-220.

8.       Multigene pathway engineering with regulatory linkers (M-PERL). Duo Liu, Hong Liu, Bingzhi Li, Hao Qi, Bin Jia, Xiao Zhou, Haoxing Du, Wei Zhang, Yingjin Yuan*. 2016, ACS Synthetic Biology, Vol 5, Issue 12:‏ 1535-1545.

9.       High production of fatty alcohols in Yarrowia lipolytica by coordination with glycolysis. Jinlai Zhang^#, Yingxiu Cao^#, Yangzi Peng, Congcong Jin, Qiuyan Bai, Ruosi Zhang, Duo Liu, Yingjin Yuan*. 2019, SCIENCE CHINA Chemistry, Vol 62, Issue 8: 1007-1016.

10.    Biosynthesis of odd-chain fatty alcohols in Escherichia coli. Yingxiu Cao, Wenhai Xiao, Duo Liu, Jinlai Zhang, Mingzhu Ding, Yingjin Yuan*. 2015, Metabolic Engineering, Vol 29: 113-123.

11.    Heterologous biosynthesis and manipulation of alkanes in Escherichia coli. Yingxiu Cao^#, Wenhai Xiao^#, Jinlai Zhang, Zexiong Xie, Mingzhu Ding, Yingjin Yuan*. 2016, Metabolic Engineering, Vol 38: 19-28.

12.    Hydrothermal pretreatment for deconstruction of plant cell wall: Part I. Effect on lignin-carbohydrate complex. Part II. Effect on cellulose structure and bioconversion. Kun Yao, Qinfeng Wu, Ran An, Wei Meng, Mingzhu Ding, Bingzhi Li, Yingjin Yuan*. 2018, AIChE Journal, Vol 64, Issue 6: 1938-1964.

13.    Directed genome evolution driven by structural rearrangement techniques. Sijie Zhou^#, Yi Wu^#, Zexiong Xie, Bin Jia, Yingjin Yuan*. 2021, Chemical Society Reviews, Vol 50, Issue 22: 12788-12807.

14.    A three-species microbial consortium for power generation. Yue Liu, Mingzhu Ding, Wei Ling, Yun Yang, Xiao Zhou, Bingzhi Li, Tao Chen, Yong Nie, Miaoxiao Wang, Boxuan Zeng, Xia Li, Hong Liu, Baode Sun, Heming Xu, Jiamei Zhang, Yi Jiao, Yanan Hou, Hui Yang, Sijia Xiao, Qucheng Lin, Xinzi He, Wenjie Liao, Zeqi Jin, Yufei Xie, Bofeng Zhang, Tianyu Li, Xi Lu, Jiabei Li, Fan Zhang, Xiaolei Wu, Hao Song*, Yingjin Yuan*. 2017, Energy & Environmental Science, Vol 10, Issue 7: 1600-1609.