SCHOOL OF CHEMICAL ENGINEERING

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教授

张 麟

现任职称/职务:教授
通讯地址:天津大学化工学院生物化工系
电子邮箱:linzhang@tju.edu.cn
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论著专利:

相关结果已发表学术论文27篇(第一作者或者通讯作者),其中SCI收录23篇,EI收录2篇,核心1篇,影响因子大于3的论文12篇,并在Chemical Society Review发表病毒样颗粒自组装研究综述。单篇最高他引28次,H因子7(他引)。已作为第一发明人获授权中国发明专利1项,申请国际专利1项和中国发明专利2项。


论文:

[1] Wenchao Zhang, Yan Sun, Lin Zhang*, Fabrication of High Efficient Silver Nanoparticle Catalyst Supported on Poly(glycidyl methacrylate)-polyacrylamide. Industrial & Engineering Chemistry Research, 2016, 55(48): 12398–12406. (SCI, EE5CY)
[2] Chao Zhang, Lin Zhang*, Youcai Zhang, Na Sun, Shaoyi Jiang, Timothy J. Fujihara, Yan Sun*, Development of antithrombotic nanoconjugate blocking integrin α2β1-collagen interactions. Scientific Reports, 2016, 6, 26292. (SCI, DM5EX)
[3] Lin Zhang, Linda HL Lua, Anton PJ Middelberg, Yan Sun, Natalie K. Connors*, Biomolecular Engineering of Virus-Like Particles Aided by Computational Chemistry Methods. Chemical Society Reviews, 2015, 44(23): 8608–8618. (SCI, CW2WI, IF 30.425)
[4] Wenchao Zhang, Yan Sun, Lin Zhang*, In Situ Synthesis of Monodisperse Silver Nanoparticles on Sulfhydryl-Functionalized Poly(glycidyl methacrylate) Microspheres for Catalytic Reduction of 4-Nitrophenol. Industrial & Engineering Chemistry Research, 2015, 54(25): 6480–6488. (SCI, CM1JG, IF 2.235)
[5] Wenchao Zhang, Lin Zhang*, Yan Sun, Size-Controlled Green Synthesis of Silver Nanoparticles Assisted by L-Cysteine. Frontiers of Chemical Science and Engineering, 2015, 9(4): 494–500. (SCI, CX5RF)
[6] Linling Yu#, Lin Zhang#, Yan Sun*, Protein behavior at surfaces: Orientation, conformational transitions and transport. Journal of Chromatography A, 2015, 1382C: 118–134. (SCI, CB6IB, IF 4.258)
[7] Lin Zhang, Ronghong Tang, Shu Bai, Natalie K. Connors, Linda HL Lua, Yap P. Chuan, Anton PJ Middelberg, Yan Sun*, Energetic changes caused by antigenic module insertion in a virus-like particle revealed by experiment and molecular dynamics simulations. PLoS ONE, 2014, 9(9): e107313–12. (SCI, AP0SM, IF 3.534)
[8] Yanying Li, Xiaodan Liu, Xiaoyan Dong, Lin Zhang*, Yan Sun*, Biomimetic Design of Affinity Peptide Ligand for Capsomere of Virus-Like Particle. Langmuir, 2014, 30(28): 8500–8508. (SCI, AL9LQ, IF 4.384)
[9] Lin Zhang, Yan Sun*, Biomimetic design of platelet adhesion inhibitors to block integrin α2β1-collagen interactions: I. Construction of affinity binding model. Langmuir, 2014, 30(16): 4725–4733. (SCI, AG3DZ, IF 4.384)
[10] Lin Zhang, Chao Zhang, Yan Sun*, Biomimetic design of platelet adhesion inhibitors to block integrin α2β1-collagen interactions: II. Inhibitor library, screening and experimental validation. Langmuir, 2014, 30(16): 4734–4742. (SCI, AG3DZ, IF 4.384)
[11] 董晓燕,刘晓丹,张麟*, 内含肽介导的鼠多瘤病毒样颗粒生产表达和纯化, 天津大学学报(自然科学与工程技术版), 2014, 47(04): 315–320. (EI, 20142117742905)
Xiaoyan Dong, Xiaodan Liu, Lin Zhang*, Intein-Mediated Expression and Purification of Murine Polyomavirus Virus-Like Particles, Journal of Tianjin University (Science and Technology) , 2014, 47(04): 315–320. (EI, 20142117742905)
[12] Lin Zhang, Ronghong Tang, Shu Bai, Natalie K. Connors, Linda HL Lua, Yap P. Chuan, Anton PJ Middelberg, Yan Sun*, Molecular Energetics in the Capsomere of Virus-Like Particle Revealed by Molecular Dynamics Simulations. Journal of Physical Chemistry B, 2013, 117(18): 5411–5421. (SCI, 143TS, IF 3.607)
[13] 白姝, 李浩, 张麟*, 静电排斥表面诱导溶菌酶分子站立, 物理化学学报, 2013, 29 (4), 849–857. (SCI, 116EB, IF 0.869)
Shu Bai, Hao Li, Lin Zhang*, Standing orientation of lysozymes induced by electrostatically repulsive surface, Acta Physico-Chimica Sinica, 2013, 29(4): 849–857. (SCI, 116EB, IF 0.869)
[14] 白姝, 唐荣宏, 张麟*, 衣壳粒蛋白稳定性的分子动力学模拟, 化学工业与工程, 2013, 30(6): 62–66. (核心)
Shu Bai, Ronghong Tang, Lin Zhang*, Molecular Dynamics Simulation of the Stability of Capsomere, Chemical Industry and Engineering, 2013, 30(6): 62–66.
[15] Lin Zhang, Yan Sun*, Effect of ligand chain length on hydrophobic charge induction chromatography revealed by molecular dynamics simulations, Frontiers of Chemical Science and Engineering, 2013, 7(4): 456–463. (SCI, V39BH)
[16] Guangjie Han, Xiaoyan Dong, Lin Zhang*, Litang Fu, Guozhen Wang, Yan Sun*, Facilitated oxidative refolding of ribonuclease A from inclusion bodies with a new redox system, Biochemical Engineering Journal, 2012, 69 (15): 106–112. (SCI, 052DS, IF 2.645)
[17] Jian Li, Lin Zhang, Yan Sun*, Molecular basis of the initial platelet adhesion in arterial thrombosis: molecular dynamics simulations, Journal of Molecular Graphics and Modelling, 2012, 37: 49–58. (SCI, 969AD, IF 2.184)
[18] Guofeng Zhao, Lin Zhang*, Shu Bai, Yan Sun*, Analysis of hydrophobic charge induction displacement chromatography by visualization with confocal laser scanning microscopy, Separation and Purification Technology, 2011, 82: 138–147. (SCI, 845OD, IF 2.775)
[19] Lin Zhang, Shu Bai, Yan Sun*, Modification of Martini force field for molecular dynamics simulation of hydrophobic charge induction chromatography of lysozyme, Journal of Molecular Graphics and Modelling, 2011, 29(7): 906–914. (SCI, 774VL, IF 2.038)
[20] Lin Zhang, Guofeng Zhao, Yan Sun*, Effects of ligand density on hydrophobic charge induction chromatography: a molecular dynamics simulation. Journal of Physical Chemistry B, 2010, 114 (6): 2203–2211. (SCI, 553GV, IF 3.603)
[21] Lin Zhang, Shu Bai, Yan Sun*, Molecular dynamics simulation of the effect of ligand homogeneity on protein behavior in hydrophobic charge induction chromatography, Journal of Molecular Graphics and Modelling, 2010, 28(8): 863–869. (SCI, 606HY, IF 2.038)
[22] Lin Zhang, Yan Sun*, Molecular simulation of adsorption and its implications to protein chromatography: a review. Biochemical Engineering Journal, 2010, 48 (3): 408–415. (SCI, 576CO, IF 2.692)
[23] Lin Zhang, Guofeng Zhao, Yan Sun*, Molecular dynamics simulation and experimental validation for the effect of pH on protein desorption in hydrophobic charge induction chromatography, Molecular Simulation, 2010, 36(13): 1096–1103. (SCI, 685KP, IF 1.215)
[24] Lin Zhang, Guofeng Zhao, Yan Sun*, Molecular insight into protein conformational transition in hydrophobic charge induction chromatography: a molecular dynamics simulation, Journal of Physical Chemistry B, 2009, 113(19): 6873–6880. (SCI, 443CP, IF 3.603)
[25] Lin Zhang, Diannan Lu, Zheng Liu*, Dynamic control of protein conformation transition in chromatographic separation based on hydrophobic interactions: Molecular dynamics simulation, Journal of Chromatography A, 2009, 1216(12): 2483-2490. (SCI, 419KH, IF 4.194)
[26] Lin Zhang, Diannan Lu, Zheng Liu*, How native proteins aggregate in solution: a dynamic Monte Carlo simulation, Biophysical Chemistry. 2008, 133(1-3): 71-80. (SCI, 268ZQ, IF 2.108)
[27] 张麟,卢滇楠,刘铮*, 高分子抑制蛋白质聚集的动态Monte Carlo模拟, 化工学报, 2008, 59(01), 153-159. (EI, 080811110678)
Lin Zhang, Diannan Lu, Zheng Liu*, Dynamic Monte Carlo simulation on protein aggregation and its inhibition by polymer, Journal of Chemical Industry and Engineering(China), 2008, 59(01), 153-159. (EI, 080811110678)
[28] 张麟,卢滇楠,刘铮*,分子动力学模拟尿素对水溶液中蛋白质构象转变的影响, 生物加工过程, 2006, 4(03), 38-43. (核心)
Lin Zhang, Diannan Lu, Zheng Liu*, The effect of urea on the conformational transition of protein in aqueous by molecular dynamics simulations, Chinese Journal of Bioprocess Engineering, 2006, 4(03), 38-43.

专利:

张麟,董晓燕,李艳英,刘晓丹,孙彦,鼠多瘤病毒衣壳粒的新型亲和肽配基及其设计筛选方法,中国发明专利,申请号201410276200X,已授权

张麟,董晓燕,李艳英,刘晓丹,孙彦,鼠多瘤病毒衣壳粒的新型亲和肽配基及其设计筛选方法,PCT,申请号PCT/CN2014/090715

张麟,孙彦,张超,针对血栓形成过程中胶原蛋白-整联蛋白α2β1相互作用的纳米抑制剂及制备方法和应用,中国发明专利,申请号201510176072.6

孙彦,张麟,张超, 胶原蛋白-整联蛋白α2β1相互作用的多肽抑制剂及筛选方法, 中国发明专利,申请号201410151205X